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- E-ISSN 2288-8985
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Article Detail
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Optimization of Response Characteristics of pH-ISFET Glucose Sensor
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1992, v.5 no.2, pp.177-184
Lee,
H. L., Yang,
S. T., Jung,
D. S., Kim,
C. S., &
Sohn,
B.
K.
(1992). Optimization of Response Characteristics of pH-ISFET Glucose Sensor. Analytical Science and Technology, 5(2), 177-184.
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Abstract
A preparation method and response characteristics of a glucose sensor which consisted of pH-ISFET and glucose oxidase-immobilized membrane were investigated. The pH-ISFET glucose sensor was fabricated by immbilizing bovine serum albumin and glucose oxidase with glutaraldehyde on gate of the pH-ISFET. Effects of pH and concentration of working buffer and enzyme load on the pontentiometric response of the pH-ISFET glucose sensor were examined. Response characteristics for the determination of glucose in synthetic physiological saline solution(pH 7.4) were as follows. That is the concentration range of linear response, slope of linear response(sensitivity), and response time were <TEX>$1.0{\times}10^{-4}{\sim}6.0{\times}10^{-3}M $</TEX>, 4.1 mV/decade, and 12~15 min., respectively.
- keywords
- Glucose sensor pH-ISFET
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