The purpose of this study was to synthesize the effects of the information literacy instruction using meta-analysis. Results using random-effect models were as follows. First, the overall average effect size (ES) of information literacy instruction (Hedges'g) was 0.72, which could be interpreted based on Cohen's guidelines as moderate to large. Second, the two types of information literacy instruction, demonstrating more than medium ESs, did not show significant differences in their ESs. Third, the ESs of information literacy instruction differed depending on the measuring variables. Fourth, grade, study design and the form of the measurement tool were moderator variables that explain the differences in ESs. In sum, the effects of information literacy instruction, having more than medium effect size, seem quite stable across instruction types and study designs.