Unlike the United States, course reserve and e-Reserve services of university libraries are very poorly operated in Korea. This paper studied cases of e-Reserve service operation of 131 university libraries in the United States to provide basic materials for revitalizing the e-Reserve service of domestic university libraries. To confirm the operation case, 131 university library websites were surveyed, and among them, the e-Reserve service operation methods of 7 university libraries were compared and analyzed, and the functions of 4 e-Reserve supporting software were checked. The research results can be used as reference materials in operating the e-Reserve service in domestic university libraries, and the function of the analyzed support software is considered to be a functional requirement to be considered when introducing the system.