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  • P-ISSN 1225-0163
  • E-ISSN 2288-8985

Identification of Antifungal Activity Subatnces on Seedborn Disease from Garlic and Taxus Extracts

Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1999, v.12 no.1, pp.47-52
Chung, III Min
Paik, Su Bong
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Abstract

Antifungal substances were isolated and identified from garlic and taxus extracts to develop safe and broad fungicide. The inhibitory effect of seedborn disease of sesame, pepper, radish, chinese cabbage by formulation of antifungal substances was investigated. The antifungal substance isolated through column chromatography from garlic and taxus extracts was confirmed by GC-MS as allicin(<TEX>$C_6H_{10}OS_2$</TEX>) and taxol(<TEX>$C_{47}H_{51}NO_{14}$</TEX>) and the quantified content from each extracts by HPLC analysis was 0.62%, 0.29%, respectively. The formulation composed of garlic and taxus extracts controlled effectively the seedborn fungi tested in this study at 10X dilution, but at 100X dilution the inhibitory effect decreased. Phytotoxicity of these formulations did not recognized.

keywords
antifungal activity, garlic, taxus, allicin, taxol, GC-MS, HPLC


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