- P-ISSN 1225-0163
- E-ISSN 2288-8985
- Log In/Sign Up
- P-ISSN1225-0163
- E-ISSN2288-8985
- SCOPUS, ESCI, KCI
Article Detail
Home > Article Detail
Validation of urinary N-methylacetamide reference material for proficiency test
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2014, v.27 no.6, pp.339-346
https://doi.org/10.5806/AST.2014.27.5.339
(2014). Validation of urinary N-methylacetamide reference material for proficiency test. Analytical Science and Technology, 27(6), 339-346, https://doi.org/10.5806/AST.2014.27.5.339
- Downloaded
- Viewed
Abstract
The author assessed the availability of urine reference material for proficiency test provided forlaboratories in occupational health. N-methylacetamide is the biomarker of exposure to N,N-dimethyl acetamide,which was used as the substitute for hepatotoxic N,N-dimethylformamide (DMF). N-methylacetamide (NMAC)urine samples of 3 different levels covering the 0.2~2 times of the exposure limit were tested. Stability testup to 180 days (0, 7, 30, 60, 180 days) at 4 different temperatures (-60, -20, 5, 25 oC) and homogeneity testwere performed for these samples. New analytical condition by GC/MSD using SIM mode (m/z 58, 59) andDB-624 column was investigated for better selectivity, sensitivity and resolution. Urinary NMAC samplesshowed good homogeneity for 3 levels. These samples also showed good stability up to 180 days. The dataof stability and homogeneity of urinary DMAC confirmed the basis of including this item into Korean proficiencytest for occupational health laboratories since 2008.
- keywords
- reference material, urinary N-methylacetamide, proficiency test, biological monitoring
Reference
1
1. ISO Reference materials - General and statistical principles for certification: ISO Guide 35: 2006 : International Organization for Standardization (2006).
2
2. Korea research institute of standards and science http://crm.kriss.re.kr/(2007).
3
3. ISO General requirements for the competence of testing and calibration laboratories: ISO/IEC 17025: Inter-national Organization for Standardization. (1999).
4
4. H. Lim, J. Ryu, S. Choi, A. Choi, H. Jung, J. Ryu, H. Kim and S. Jang, Anal. Sci. Technol., 22(5), 369-375(2009).
5
5. C.-H. Jung, D.-W. Park, S.-M. Kim and E.-C. Yu, Anal. Sci. Technol., 22(1), 82-91 (2009).
6
6. EA The selection and use of reference materials: EA-4/14 (rev.00): European co-operation for Accreditation. (2003).
7
7. J.-S. Yang, Proficiency test program for biological samples for biological monitoring, Korea safety and health agency (1995).
8
8. Practical guide for health examination of workers. Korea safety and health agency. Ministry of labour (2013).
9
9. J.-S. Yang, D. H. Sohn, M.-Y. Lee, S.-K. Kang, Preparation method of reference material for analysis of metabolite of organic solvents in urine. Patent No. 165621, Korean Intellectual Property Office (1998).
10
10. R. Lawn, P. Roper, G. Holcombe, B. Stuart, Low-cost QC laboratory reference materials - Investigation of cost-effective production procedures: LGC/VAM/2001/009: LGC (2001).
11
11. R. Lawn, P. Roper, G. Holcombe and B. Stuart, Application notes for the production of low-cost quality control matrix reference materials: LGC/VAM/2001/010:VAM (2001).
Other articles from this issue
- A short study of uncertainty for post column isotope dilution method in HPLC-ICP/MS
- Effect of concentration, pressure, and cut-off size on removing phospholipase A2 in bee venom by ultrafiltration
- VOCs impact factor analysis of unit components in Part assembly by ISO 12219-5 method
- Structural characterization and degradation efficiency of degradation products of iopromide by electron beam irradiation
- The application of a chemical assessment of archaeological animal bone by Fourier transform infrared spectroscopy and x-ray diffraction
- The characteristics of dye-sensitized solar cells using carbon nanotube in working and counter electrodes
- Microwave-modified sol-gel preparation of La2(MoO4)3:Er3+/Yb3 particles and their upconversion photoluminescence properties
- Distribution characteristics of hexabromocyclododecanes in crucian carp and sediment from the major rivers
- Validation of analysis of urinary fluoride by ion selective electrode method
- Validation of urinary N-methylacetamide reference material for proficiency test
- PCDDs and DFs concentrations from the fly ash and bottom ash of industrial waste incinerators in Korean
- Determination of boron in steel by HNO3-NH4HF2 digestion and ICP-MS
- Preparation and characterization of the primary gas standards for isoprene
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.