- P-ISSN 1225-0163
- E-ISSN 2288-8985
유기게르마늄 화합물인 Ge-132의 분석법을 확립하였다. 이온교환수지 컬럼을 사용하고 <TEX>$Na_2B_4O_7$</TEX> buffer를 이동상으로 하여 Ge-132를 분리한 다음, 전기전도도 검출기를 사용하여 검출하는 방법을 이용한 결과 50pmol의 농도까지 분석할 수 있었다. 이 방법은 Ge-132의 원료와 제품의 품질 관리에 응용이 가능하였다.
An organic germanium compound, Ge-132, was reported to have interferon inducer activity, anti-tumor activity and anti-viral activity. ICP, AA and colorimetry methods were used for the determination of germanium in Ge-132. However these methods have a problem that they only give an information on the total amount of germanium element, and consequently Ge-132 connot be distinguished form toxic inorganic Ge compounds. To overcome this problem, ion chromatography was used to analyze Ge-132. Ge-132 was separated on Ionpac AS4A column with 1.3mM <TEX>$Na_2B_4O_7$</TEX> buffer(pH