This study examined moderating effect of proactive personality on the relation of job autonomy, social support, job engagement and job burnout among female workers. Furthermore, the structural relations were compared between female office workers and labor workers. Survey data from 371 female workers over the age of 19, out of them, 244 were office workers and 127 were labor workers. Data were analyzed using structural equation modeling. The results of this study showed that the relation of job autonomy, social support, job engagement and job burnout were significanttly moderated by proactive personality. The results of multi-group analysis also indicated that the structural model differed between the two groups. Implications and limitations of this study and counseling intervention for female workers in Korea are discussed.