Despite the recent increase in the incidence rate of non-suicidal self-injury( NSSI) among college students, there are still no active reports of standardized treatments targeting college students with non-suicidal self-injurious behaviors in Korea. In this study, we developed 10-session short-term DBT program that complemented the realistic limitations of time and costs of existing long-term dialectical behavior therapy (DBT) and then applied a short term DBT to two female college students. Case 1 was an instance where negative automatic thoughts triggered by work-related stress and conflict with parents led to self-loathing. This evolved into an overwhelming state of negative emotions, where impulses for self-injury developed into actual self-injury behavior. The intervention focused on cognitively recognizing the vulnerability factors, triggers, and links that led to these target behaviors, emphasizing self-monitoring and the application of crisis management skills. In Case 2, the individual engaged in self-injury as a form of punishment, driven by self-criticism in situations of interpersonal stress. The focus was on delaying and stopping self-injury behavior through mindfulness of emotional states and non-judgmental thinking in the process leading up to the appearance of self-injury impulses and self-injury behavior. In both cases, by the practice of using chain analysis of non-suicidal self-injurious behavior, they realized the link between their target behavior and succeeded in delaying or stopping the target behavior by applying emotion regulation skills in an attempt to break this link. The effectiveness of this short-term DBT program for reducing non-suicidal self-injury behavior should be proven through the accumulation of more cases and comparative studies in the future.