This study aims to investigate the mediating effects of perceived social support in the relationship between work-family conflict and job satisfaction among married female managers. For this purpose, data from the 2020 1st Korean Women Manager Panel Survey were utilized. Firstly, work-family conflict exerted a statistically significant negative effects on the job satisfaction. Secondly, the work-family conflict had a significant negative effects on their perceived social support. Also, perceived social support demonstrated statistically significant positive effects on job satisfaction. Thirdly, in the context of the relationship between work-family conflict and job satisfaction, organizational support, supervisor support, and spouse support exhibited the multiple parallel mediating effects. It was observed that the mediating effects of job-related support were larger than those of non-job-related support. Drawing from these research findings, practical strategies for enhancing the job satisfaction of married female managers were discussed.