Purpose: Despite significant commitments between corporations and the government on green supply chain, green logistics and sustainable production, the adoption of green and sustainable trading innovation in Vietnam continues to face many obstacles. The objective of thisstudy isto approach the decision to adopt green and sustainable trading innovation from the perspective of the enterprise. Research Design, Methodology and Approach: A cross-sectional study with the participation of 651 employees and managers at distribution enterprises such as logistics, supply, and delivery enterprises in southern Vietnam was conducted to assess business innovation decisions through innovation awareness. Partial least squares structural equation modelling (PLS-SEM) was proposed to evaluate the structural relationships of the model. Results: The research results show that the decision to innovate an enterprise is directly positively affected by the perception of marketing innovation, process innovation and organizational innovation; in which process innovation and organizational innovation are mediators for the perception of marketing innovation. Conclusions: This study makes a significant contribution by demonstrating the impact of marketing innovation awareness on the entire process that leads to enterprise innovation decisions to fulfil customer expectations and competitive pressure in the context of the green supply chain, green logistics and sustainable production.