Due to the COVID-19 pandemic, scholars at institutions of higher education around the world are transitioning their teaching, service, and research into online settings; for many this may be a new and challenging experience. While many of the best practices associated with research in traditional or face-to-face settings also apply to research in or via online settings, there are some additional challenges and nuances that researchers must adequately address and plan for due to the affordances and limitations of online settings. This paper discusses the key issues of privacy, informed consent, trust and trustworthiness, and retention through the literature and provides practical recommendations based on evidence and experience from two different online research projects. The reflections on and examples from these two research projects contextualize the above issues and act as evidence to inform research as a practice. The authors hope this evidence and practical guidance may help researchers better prepare for research in a socially distanced world.