Historically, mothers have been noted as active health information seekers, reflecting their roles as health mangers and caregivers for their family members. However, previous studies have focused on health-related information behavior among mothers in native populations or mothers of children with specific diagnoses. To fill this research gap, this study focused on health information behavior among mothers of healthy infants and toddlers. Using Wilson’s (1997) information-seeking model, this study aimed to uncover the relationships between mothers’ demographic characteristics and their health information source use. Online surveys were completed by 851 mothers: 255 U.S.-born mothers, 296 Korean-born mothers, and 300 Korean immigrant mothers living in the United States. Results indicated that there were statistically significant relationships between mothers’ nine demographic characteristics (mother’s age, education level, household income, employment status, the number of children, years living in the U.S. (or Korea), fluency in speaking English, size of household, housing status) and their health information source use. Based on the results, the implications for information professionals at diverse organizations are discussed when they provide health information services to this specific population.