ISSN : 1226-9654
This study examined effects on acquisition and retention of conditioned fear of nucleus accumbens(n.Acc) lesion and central amygdaloid nucleus(ACe) lesion. The suppression ratio in bar-pressing of ACe-lesioned group was compared with that of Sham-Conditioning group and Sham-Control group. In n.Acc groups same comparisions were made respectively. If was found that ACe-lesioned animals and n.Acc-lesioned animals showed the deficit in acquisition of conditioned fear. It was suggested that ACe seemed to be essential in the formation of associations between motivationally significant stimuli and that mesolimbic dopamine system was involved in the activation of behavior by motivationally significant stimuli.