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ISSN : 1226-9654

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Vol.7 No.1

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Effects of capsaicin on nociceptive responses and open-field behaviors in adult rats

The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
1995, v.7 no.1, pp.106-115
Soon-Kwon Park (Department of Psyology, Korea University)
Hyun-Taek Kim (Department of Psyology, Korea University)
Heung-Sik Na (Department of Physiology, College of Medicine, Korea University)
Seung-Kil Hong (Department of Physiology, College of Medicine, Korea University)
Park, S., Kim, H., Na, H., & Hong, S. (1995). Effects of capsaicin on nociceptive responses and open-field behaviors in adult rats. The Korean Journal of Cognitive and Biological Psychology, 7(1), 106-115.

Abstract

We investigated the effects of capsaicin(s.c. 150mg/kg) on the open-field behaviors and the thresholds and latency of nociceptive responses in adult rats. Results are as follows. 1) Capsaicin did not affect open-field behaviors. It hints that capsaicin did not alter the emotionality and motor function of rats. 2) Whereas the threshold of jumping was elevated, those of fore and hind paw licking were not in animals treated with capsaicin. Capsaicin also enhanced hind paw licking latency to thermal stimulus over thershold in hot plate test. These results suggest that capsaicin affects the coping reaction to strong thermal stimulus, but not adaptive reaction to mild stimulus, in adult rats.

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The Korean Journal of Cognitive and Biological Psychology

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