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ISSN : 1226-9654

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Effects of Reserpine on the Isolation-Induced Hyperaggression in Mice

The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
1989, v.1, pp.26-33
Hyoun-Kab Chang (Yeungnam University)
Soon-Kwon Park (Yeungnam University)
Sung-Gun Kang (Yeungnam University)
Chang, H., Park, S., & Kang, S. (1989). Effects of Reserpine on the Isolation-Induced Hyperaggression in Mice. The Korean Journal of Cognitive and Biological Psychology, 1, 26-33.

Abstract

The purpose of this study was to determine the effects of reserpine treatment on the isolation-induced hyperaggression in A/J strain of albino mice. Male mice were separated from their own litters on the weaning day(21±1 days) and reared in isolation or in group for 57days. The behavioral index of aggression is the tail-rattling(TR) response to the opponent animal surrounded by a wire screen. In the pretest, both isolation and group animals were exposed to the opponent animal and TR responses were observed. Mice which showed TR response in the pretest were tested after reserpine(2.5mg/kg) injection. The present results are as follows: 1) isolation-reared animals showed higher aggression than those of group-reared animals in the pretest 2) reserpine treatment effectively reduced the occurrence of TR response in both isolation-reared and group-reared animals. These results are consistent with our previous study(Chang, et al., 1988) that diazepam treatment decreased the isolation-induced hyperaggression.

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Submission Date
1989-10-13
Revised Date
1989-11-05
Accepted Date

The Korean Journal of Cognitive and Biological Psychology

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