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ISSN : 1226-9654

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Vol.11 No.1

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The electrolytic lesion effects of prelimbic area and anterior cingulate cortex of medial prefrontal cortex on delayed spatial win-shift task using 8-arm maze with rats : anterior cingulate cortex is involved in memory demanding tasks

The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
1999, v.11 no.1, pp.45-58
Younghwa Yoon (Korea Neuropsychological Research Institute)
Hyuntaek Kim (Dept. of Psychology, Korea University)
Yoon, Y., & Kim, H. (1999). The electrolytic lesion effects of prelimbic area and anterior cingulate cortex of medial prefrontal cortex on delayed spatial win-shift task using 8-arm maze with rats : anterior cingulate cortex is involved in memory demanding tasks. The Korean Journal of Cognitive and Biological Psychology, 11(1), 45-58.

Abstract

This study investigated the role of prelimbic area (PL) and anterior cingulate cortex (ACC) of medial prefrontal cortex using two delayed spatial win-shift (SWS) tasks and a single-phase random foraging task on an 8-arm radial maze. Delayed SWS task consisted of a training and a test phase separated by a delay period (5 min. in the 1st task and 30 min. in the 2nd task). PL-lesioned animals learned all the 3 tasks as well as the control animals. However ACC-lesioned animals revisited previously baited arms in the training and the test phase but they achieved performance criterion in the 1st task. ACC-lesioned animals showed no impairment in the 2nd or the 3rd task. These data suggest that PL is involved neither in working memory nor spatial learning and that ACC is important in memory demanding tasks. The effects of lesions of the ACC diminished as the training progressed. ACC appears to be of particular importance for a difficult task in a new and challenging situation.

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The Korean Journal of Cognitive and Biological Psychology

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