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Types of Associative Memory Task and Hippocampal Activations: an fMRI Study

The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
2005, v.17 no.4, pp.477-498






Abstract

In this study, two different associative memory tasks were compared in order to elucidate the types of associative memory in which hippocampus is involved. Brain regions activated during encoding and/or recognition of associative memories were investigated with fMRI in two different associative memory tasks with normal heathy volunteers (N=16). Depending on the types of the task, an namable line-drawing object was to be remembered with its presentation position (left/right) (object-position task) or with arbitrarily paired another object (object-object task). In comparison to fixation rest condition, hippocampus was activated both during encoding and recognition of the object-object associative memory task, but not during the object-position associative memory task. Various cortical regions were activated in both associative tasks, including visual cortex, parietal and prefrontal regions, and cingulate. However, the superior colliculus activation was found in the right hemisphere only during the object-position associative memory task, in which spatial attention or search might be required. These findings suggested that hippocampus is selectively involved in associative memory tasks depending on the types of information to be memorized.

keywords
연합기억, 해마, 상소구, associative memory, hippocampus, superior colliculus, fMRI

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The Korean Journal of Cognitive and Biological Psychology