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Effects of Central Amygdaloid Nucleus Lesion on the Development of Stomach Ulcers Induced by a Conflict - Stress in Rats

The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
1990, v.2, pp.100-108
Jong-Taeg Yi (Korea University)
Ki-Suk Kim (Korea University)

Abstract

This experiment was conducted to answer the question whether or not the lesion of central amygdaloid nucleus inhibites the development of a conflict stress induced stomach ulcer, 40 rats were randomly assigned into two groups, that is, a central amygdaloid nucleus lesion group and a sham - operationed group. One week after surgery, they were put in Skiner Box and received electric shock as a conflict stress. After the experiment, the stomach was removed as soon as possible. The lesion group had inhibited significantly the development of stomach ulcer, whereas the sham - operated group did not inhibit the development of the ulcer. The results suggest that the central amygdaloid nucleus is a neural substrate that responds to the conflict stress as well as any other type of stress.

keywords

The Korean Journal of Cognitive and Biological Psychology