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Aluminium Induced Distant Lesions in Rats - A Descriptive Anatomical Study -

Aluminium Induced Distant Lesions in Rats - A Descriptive Anatomical Study -

한국심리학회지: 인지 및 생물 / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
1990, v.2, pp.94-99
P. Calabreses (University of Bochum)
J.I. Kim (University of Bochum)
H.J. Markowitsch (University of Bochum)

Abstract

The role of aluminium as a neurotoxic agent has been demonstrated in many independent investigations. In our study, chronic intoxication of the rat CNS produced by epidural application of an aluminium salt led to neuronal degeneration of tissue distal to the primary lesion. Furthermore, the alterations seem to be restricted to distinct populations of neurons. Preliminary neuropathological data are reported.

keywords
rat, aluminium, chronic intoxication, distant lesions neuronal degeneration

한국심리학회지: 인지 및 생물