Central Amygdala and Immobilization Stress-Induced Gastric Pathology in Rats: Dopamine and haloperidol
The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
1991, v.3, pp.32-40
Hyoun-Kab Chang
(Yeungnam University)
Byung-Soo Yoon
(Yeungnam University)
Chang,
H., &
Yoon,
B.
(1991). Central Amygdala and Immobilization Stress-Induced Gastric Pathology in Rats: Dopamine and haloperidol. The Korean Journal of Cognitive and Biological Psychology, 3, 32-40.
Abstract
The present study was undertaken to investigate the effects of dopamine(10㎍), haloperidol(10㎍) and saline injected bilaterally into the central amygdala. After drug treatment the rats were immobilized individually in supine-restraint devicers at 4℃ for 3hr. The results were as follows: DA had an attenuating effect on gastric ulcers, but haloperidol had and aggravating effect. These results indicate the central amygdala is important in the mediation of the ulcer attenuating effect of dopamine.