바로가기메뉴

본문 바로가기 주메뉴 바로가기

logo

Dissociation between categorization and recognition in the Alzheimer's and Parkinson's disease patients

The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
2013, v.25 no.3, pp.311-327
https://doi.org/10.22172/cogbio.2013.25.3.004



  • Downloaded
  • Viewed

Abstract

We investigated whether the dissociation between categorization and recognition are occurred in the elderly, Dementia of the Alzheimer's Type and Parkinson's disease patients by using the learning-transfer phase experimental paradigm and dot patterns as experimental material. While Knowlton and Squire(1993) used different items(dot patterns) in the transfer stages in categorization task and recognition task, we used the same items in both categorization and recognition transfer stage to compare the results with each other directly. The results showed that recognition is impaired in the elderly and Dementia of the Alzheimer's Type patients, while categorization is preserved. However, there is no difference in performance between Parkinson's disease patients and controls on categorization and recognition. The clinical implications of these results were discussed in the final section.

keywords
범주화, 재인, 해리, 점패턴 과제, 알츠하이머병, 파킨슨병, categorization, recognition, dissociation, dot-pattern task, Dementia of the Alzheimer's Type, Parkinson's disease

Reference

1.

강연욱, 나덕렬, 한승혜 (1997). 치매환자들을 대상으로 한 K-MMSE의 타당도 연구. 대한신경과학회지, 15(2), 300-308.

2.

최성진, 신현정 (2009). 노화와 뇌손상에 따른 범주화와 재인기억의 해리: 대학생과 노인, 알츠하이머형 치매 환자를 대상으로. 한국심리학회지: 일반, 28(1), 67-82.

3.

최성진, 홍창희, 신현정 (2007). 처리수준에 따른 외현기억과 암묵기억의 해리: 대학생, 노인, 알츠하이머형 치매, 파킨슨병 환자를 대상으로. 한국심리학회지: 실험, 19(2), 93-111.

4.

Ashby, F. G., Alfonso-Reese, L. A., Turken, A. U., & Waldron, E. M. (1998). A neuropsychological theory of multiple systems in category learning. Psychological Review, 105, 442-481.

5.

Ashby, F. G., & Maddox, W. T. (2005). Human category learning. Annual Review of Psychology 5, 149-178.

6.

Brown, R. G., & Marsden, C. D. (1988). Internal versus external cues and the control of attention in Parkinson's disease. Brain, 111, 323-345.

7.

Clark, U. S., Neargarder, S., & Cronin-Golomb, A. (2010). Visual exploration of emotional facial expressions in Parkinson's disease. Neuropsychologia, 48, 1901-1913.

8.

Cohen, N. J., & Squire, L. R. (1980). Preserved learning and retention of pattern analyzing skill in amnesics: Dissociation of knowing how and knowing that. Science, 210, 207-210.

9.

Cummings, J. L. (1986). Subcortical dementia: Neuropsycholgy, neuropsychiatry, and pathophysiology. British Journal of Psychiatry, 149, 682-697.

10.

Curran, T. & Schacter, D. L. (1996). Implicit memory and perceptual brain mechanisms. Basic and applied memory research: Theory in context. 1, 221-240.

11.

deToledo-Morrell, L., Sullivan, M. P., Morrell, F., Wilson, R. S., Bennett, D. A., & Spencer, S. (1997). Alzheimer’'s disease: In vivo detection of differential vulnerability of brain regions. Neurobiology of Aging, 18, 463-468.

12.

Dormal, V., Grade, S., Mormont, E., & Pesenti, M. (2012). Dissociation between numerosity and duration processing in aging and early Parkinson's disease. Neuropsychologia, 50, 2365-2370.

13.

Dubois, B., & Pillon, B. (1997). Cognitive deficits in Parkinson's disease. Journal of neurology, 244, 2-8.

14.

Egly, R., & Homa, D. (1984). Sensitization of the visual field. Journal of Experimental Psychology: Human Perception& Performance, 10, 778-793.

15.

Fleischman, D. A., Wilson, R. S., Gabrieli, J. D., Schneider, J. A., Bienias, J. L., & Bennett, D. A. (2008). Implicit memory and Alzheimer's disease neuropathology. Brain, 128, 2006- 2015.

16.

Gabrieli, J. D. (1996). Memory systems analyses of mnemonic disorders in aging and age-related disease. Proceedings of the National Academy of Sciences of the United States of America, 93, 13534-13540.

17.

Gilbert, C. D. (1998). Adult cortical dynamics. Physiological Reviews, 78, 467-485.

18.

Hoehn, M. M., Yahr, M. D. (1967). Parkinsonism: onset, progression, and mortality. Neurology, 17, 427-442.

19.

Hughes, C. P., Berg, L., Danziger, W. L., Cober, L. A., & Martin, R. L. (1982). A new clinical scale for the staging of dementia. British Journal of Psychiatry, 140, 556-572.

20.

Ishii, K., Kitagaki, H., Kono, M., & Mori, E. (1996). Decreased medial temporal oxygen metabolism in Alzheimer's disease shown by positron emission tomography. Journal of Nuclear Medicine, 37, 1159-1165.

21.

Jahanshahi, M., Brown, R. G., & Marsden, C. (1992). The effect of withdrawal of dopaminergic medication on simple and choice reaction time and the use of advance information in Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry, 55, 1168-1176.

22.

Java, R. L., & Gardiner, J. M. (1991). Priming and aging: Further evidence of preserved memory function. American Journal of Psychology, 104, 89-100.

23.

Keri, S., Kalman, J., Kelemen, O., Benedek, G., & Janka, Z. (2001). Are Alzheimer's disease patients able to learn visual prototypes? Neuropsychologia, 39, 1218-1223.

24.

Keri, S., Kalman, J., Rapcsak, S. Z., Antal, A., Benedek, G., & Janka, Z. (1999). Classification learning in Alzheimer's disease. Brain, 122, 1063-1068.

25.

Knowlton, B. J., Mangels, J. A., & Squire, L. R. (1996). A neostriatal habit learning system in humans, Science, 273, 1399-1402.

26.

Knowlton, B. J., & Squire, L. R. (1993). The learning of categories: Parallel brain systems for item memory and category knowledge. Science, 262, 1747-1749.

27.

Knowlton, B. J., Squire, L. R., & Gluck, M. A. (1994). Probabilistic classification learning in amnesia. Learning and Memory, 1, 106-120.

28.

Knowlton, B. J., Squire, L. R., Paulsen, J. S., Swerdlow, N. R., Swenson, M., & Butters, N. (1996). Dissociations within nondeclarative memory in Huntington’'s disease. Neuropsychology, 10, 538-548.

29.

Light, L. L., & Singh, A. (1987). Implicit and explicit memory in young and older adults. Journal of Experimental Psychology: Learning, Memory, and Cognition, 13(4), 531-541.

30.

McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stradlan, E. M. (1984). Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology, 34, 939-944.

31.

Martins, C. A., & Lloyd-Jones, T. J. (2006). Preserved conceptual priming in Alzheimer's disease. Cortex, 42, 995-1004.

32.

Mori, E., Yoneda, Y., Yamashita, H., Hirono, N., Ikeda, M., & Yamadori, A. (1997). Medial temporal structures related to memory impairment in Alzheimer's disease: an MRI volumetric study. Journal of Neurology, Neurosurgery, and Psychiatry, 63, 214-221.

33.

Posner, M. I., Goldsmith, R., & Welton, K. E. (1967). Perceived distance and the classification of distorted patterns. Journal of Experimental Psychology, 73, 28-38.

34.

Reber, P. J., Gitelman, D. R., Parrish, T. B., & Mesulam, M. M. (2003). Dissociating explicit and implicit category knowledge with fMRI. Journal of Cognitive Neuroscience, 15, 574-583.

35.

Reber, P. J., Stark, C. E. L., & Squire, L. R. (1998). Cortical areas supporting category learning identified using functional MRI. Proceedings of the National Academy of Sciences of the USA, 95, 747-750.

36.

Reber, P. J., & Squire, L. R. (1999). Intact learning of artificial grammars and intact category learning by patients with Parkinson's disease. Behavioral Neuroscience, 113, 235-242.

37.

Reed, J. M., Squire, L. R., Patalano, A. L., Smith, E. E., & Jonides, J. (1999). Learning about categories that are defined by objects like stimuli despite impaired declarative memory. Behavioral Neuroscience, 113, 411-419.

38.

Saint-Cyr, J. A., Taylor, A. E., & Lang, A. E. (1988). Procedural learning and neostrial dysfunction in man. Brain, 111, 941-959.

39.

Schacter, D. L. (1987). Implicit memory: History and current status. Journal of Experimental Psychology: Learning, Memory, and Cognition, 13, 501-518.

40.

Schacter, D. L., & Tulving, E. (1994). What are the memory systems of 1994? In D. L. Schachter & E. Tulving (Eds.), Memory systems of 1994. Cambridge, MA: MIT Press.

41.

Squire, L. R. (1992). Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans. Psychological Review, 99, 195-231.

42.

Squire, L. R., & Knowlton, B. J. (1995). Learning about categories in the absence of memory. Proceedings of the National Academy of Science, 92, 12470-12474.

43.

Zanetti, O., Binetti, G., Magni, E., Rozzini, L., Bianchetti, A., & Trabucchi, M. (1997). Procedural memory stimulation in Alzheimer's disease: impact of training programme. Acta Neurolgica Scandinavica, 95, 152-157.

44.

Zhang, Y., Tosun, D., Mojabi, P., Nezamzadeh, M., Zhan, W., Shirley, C., Kang, G., Glass, G., Marks, W., Weiner, M. W., & Schuff, N. (2010). Dissociated gray matter atrophy and hypoperfusion in Alzheimer's disease and Parkinson's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 6, S426.

The Korean Journal of Cognitive and Biological Psychology