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ISSN : 1226-9654

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Effects of apomorphine on extinction of rabbit's classically conditioned NMR, hippocampal MUA, hippocampal θ rhythm

The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
1991, v.3, pp.53-64
Doo-Hyun Lee (Korea University)
Jae-Wook Ryou (Korea University)
Jae-Il Kim (Korea University)
Ki-Suk Kim (Korea University)
Lee, D., Ryou, J., Kim, J., & Kim, K. (1991). Effects of apomorphine on extinction of rabbit's classically conditioned NMR, hippocampal MUA, hippocampal θ rhythm. The Korean Journal of Cognitive and Biological Psychology, 3, 53-64.
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Abstract

In this study, interactions among hippocampal θ rhythm, hippocampal MUA, and dopamine pathway that ascends to medial septum from brain stem reticular formation was investigated. First, rabbit`s NMR were conditioned with delay conditioning procedure. In extinction session, the one group(apomorphine group) was treated with apomorphine(0.5mg/kg) which was known to be dopamine agonist. The other group(lesioned group) was lesioned medial septum after delay conditioning and was treated as the former group. The control group was extincted conditioned response without any other procedures. There were increses of type 1 θ rhythm only in apomorphine group, but a little conditioned response in contrast to any other group. This result suggest that the apomorphine brought about type 1 hippocampal θ rhythm and kept conditioned response from being retrieve rather than being extincted.

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The Korean Journal of Cognitive and Biological Psychology

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