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ISSN : 1226-9654

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Vol.8 No.1

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Effects of Medial and Lateral Septal Lesions on Expression of Anxiety in an Elevated Plus-Maze in Rats

The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
1996, v.8 no.1, pp.39-48
Bong-Kyo Chung (Yeungnam University)
Byung-Soo Yoon (Yeungnam University)
Chung, B., & Yoon, B. (1996). Effects of Medial and Lateral Septal Lesions on Expression of Anxiety in an Elevated Plus-Maze in Rats. The Korean Journal of Cognitive and Biological Psychology, 8(1), 39-48.

Abstract

This study was conducted to examine the role of medial and lateral septum in expression of anxiety in rats. Effects of medial and lateral septal lesions were compared in an elevated plus-maze. Rats were divided into sham-operated, medial septal lesions and lateral septal lesions. Half of the animals in each group were administered 2mg/kg diazepam 20 minutes prior to the plus-maze test. Injection of diazepam increased open-arm exploration in sham-operated animals. Septal lesions increased open-arm exploration, but there was no difference in performance between medial and lateral lesions. This results suggested the septum control the expression of anxiety, but the proposition that medial septum and the lateral septum indepedently control the expression of anxiety was not supported.

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The Korean Journal of Cognitive and Biological Psychology

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