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  • P-ISSN1226-9654
  • E-ISSN2733-466X
  • KCI

ISSN : 1226-9654

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Vol.30 No.1

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Memory Consolidation or Reconsolidation for the Treatment of Posttraumatic Stress Disorder

The Korean Journal of Cognitive and Biological Psychology / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
2018, v.30 no.1, pp.1-14
https://doi.org/10.22172/cogbio.2018.30.1.001


& (2018). Memory Consolidation or Reconsolidation for the Treatment of Posttraumatic Stress Disorder. The Korean Journal of Cognitive and Biological Psychology, 30(1), 1-14, https://doi.org/10.22172/cogbio.2018.30.1.001

Abstract

Memory is labile immediately upon acquisition and becomes stable over time, and this process is called memory consolidation. If retrieved, previously-consolidated memory becomes labile again and re-consolidates. Thus, memory can be altered by intervening in either the consolidation or reconsolidation process. Propranolol is one promising drug that can block memory consolidation and reconsolidation. The present article reviewed basic research on memory consolidation and reconsolidation, and clinical trials of propranolol for the prevention and treatment of posttraumatic stress disorder. Clinical studies are currently mixed with positive and negative results, and future research is warranted on boundary conditions in which memory reconsolidation occurs. Finally, ethical issues of using memory-altering drugs are discussed.

keywords
기억 응고화, 재응고화, 프로프라놀롤, 외상후 스트레스장애, emory consolidation, reconsolidation, propranolol, PTSD

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