CAD has been the most critical cause of death in industrialized countries. Traditionally. smoking. hypertension, and hypercholesterolemia have been recognized as the most critical risk factors to CAD. Since mid 70s. however. Type A behavioral pattern became one of the critical risk factors to CAD. Thus, the present study reviewed selected articles on the relations between the onset of CAD and Type A behavioral pattern, then it was concluded that hostility is the most critical risk factor to the onset of CAD among the various components of Type A behavioral pattern. In addition. an attempt was also made to review some articles shading lights on the possible prevention from Type A behavioral pattern for the healthy people and/or intervention of the Type A behavioral pattern for the CAD patients. Finally. some implications for future prospects are suggested in this area.