The purpose of this study was to analyze the relationship between drinking problems and psychosocial risk factors, and to identify the determinant to develop prediction model among them. In the first part of the study, the twenty five candidates for determining factors are investigated through the 'Data Mining Answer Tree' with 212 students and 386 adults. In the other part of this study, nine determinants derived from analysis 1-presonality (extraversion, novelty seeking, anxiety & hostility), peer pressure(exposure to family & peer group), drinking motivation(enhancement, coping & social motive) - are compared through the 'Neural Connection'. And then those results are discussed in terms of clinical utility in the prediction and prevention of alcohol misuse and it's problem.