This study examined the effects of catastrophizing and neuroticism on experimental pressure pain threshold. Catastrophizing subscale of Coping Strategies Questionnaire (CSQ; Rosenstiel & Keefe, 1983) and The Korean version of the Eysenck Personality Scale-Adult were administered to 130 undergraduate students. The final sample consisted of eighty-eight students in this study and pressure pain thresholds were measured at middle forearm. middle phalanx, and tibia The results suggested that catastrophizing and sex were associated with individual differences in pressure pain thresholds, but neuroticism was not. Further, there was significant interaction between catastrophizing and sex. The discussion addresses the mechanisms by which catastrophizing may contribute to pressure pain threshold, and clinical implications of these results are discussed in relation to pain therapy.