바로가기메뉴

본문 바로가기 주메뉴 바로가기

ACOMS+ 및 학술지 리포지터리 설명회

  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
사전등록 바로가기
 

logo

논문 상세

이전 다음
논문 투고

Vol.9 No.3

Citation Share

스트레스 호르몬인 타액 코티졸과 자기보고식 스트레스 척도 점수 사이의 관계

The Relationship between the stress hormone, salivary cortisol level and stress score by self-report measurement

한국심리학회지: 건강 / The Korean Journal of Health Psychology, (P)1229-070X; (E)2713-9581
2004, v.9 no.3, pp.633-646
김동수 (공군사관학교)
정연수 (공군사관학교)
박세권 (공군사관학교)
김동수, 정연수, & 박세권. (2004). 스트레스 호르몬인 타액 코티졸과 자기보고식 스트레스 척도 점수 사이의 관계. 한국심리학회지: 건강, 9(3), 633-646.

초록

건강한 젊은 남자, 여자인 사관생도를 대상으로 심리적 스트레스 정도와 스트레스의 생리적 척도 중 하나인 타액 내 코티졸을 정량하여 비교 분석함으로서 만성적 생활스트레스의 척도간 상관관계를 연구하였다. 타액 코티졸의 양과 스트레스 총점에서의 개인차는 정적 상관성(r=0.319)을 나타내었으나 호환성은 없었다. 그러나 타액 코티졸의 양이 상대적으로 높은 상위 25%에 해당하는 개인들의 스트레스 총점과 타액 코티졸을 비교했을 때 상관계수가 r=0.626으로 높은 상관성을 나타내었다. 즉 건강한 집단에서 자기보고식 스트레스 척도는 생리적 척도와 직접 비교되지 못하나 상대적으로 높은 생활 스트레스(>8.5 ng/ml 타액 코티졸)를 경험하는 조건에서는 상호호환이 가능함을 보고한다. 또한, 심리적 스트레스가 상대적으로 높았던 2학년 생도들이 3학년 생도들에 비하여 유의미하게 높은 타액 코티졸 수준을 보이며 (p<0.002), 반대로 유의미하게 낮은 수의 백혈구(p<0.02), 적혈구(p<0.03)를 보유하고 있었다. 스트레스 정도가 심한 2학년 집단은 정상수치보다 낮은 혈구를 가지고 있음으로서 스트레스의 생리적 반응이 정상상태에서도 면역기능과 연관됨을 알 수 있었다.

keywords
life stress, salivary cortisol, psychoneuroimmunology, leukocytes, life stress, salivary cortisol, psychoneuroimmunology, leukocytes, 생활스트레스, 타액 코티졸, 심리신경면역, 혈구세포

Abstract

We investigated correlation between psychological stress level and one of the physiological stress biomarkers, salivary cortisol level of healthy men and women, cadets of Air Force Academy. Salivary cortisol level of individuals correlated positively with psychological stress test score (r=0.319), but it could not compatible in normal healthy individuals. On the contrary, salivary cortisol level correlated highly with psychological stress test score in individuals, who belongs to the upper 25% group based on their salivary cortisol level (r=0.626). We report that psychological stress score based on self reporting and salivary cortisol level may not be compatible in healthy men and women, however, quantitative scales come from both of measurements can be used for same purpose in some of healthy individual with relatively higher stress level(>8.5 ng/ml cortisol). In comparison between groups, second grade cadets with relatively higher score in psychological stress test had significantly higher salivary cortisol level than third year cadets with relatively low stress score in psychological stress test (p<0.002). Second grade cadets had significantly lower number of white blood cells (p<0.02) and red blood cells (p<0.03) than third year cadets. We supposed that physiological reponses against to life stressors may relate to immunity in normal situation because second grade cadets represented higher stress level had lower number of blood cells.

keywords
life stress, salivary cortisol, psychoneuroimmunology, leukocytes, life stress, salivary cortisol, psychoneuroimmunology, leukocytes, 생활스트레스, 타액 코티졸, 심리신경면역, 혈구세포

참고문헌

1.

(2000) 개정판 대학생용 생활 스트레스 척도 개발 연구,

2.

(1989) A molecular basis for bidirectional communication between the immune and neuroendocrine systems,

3.

Dantzer, R., , (1998) Cytokines and sickness behavior.,

4.

(1996) Surgical stress induces a shift in the type-1/type-2 T-helper cell balance, suggesting down-regulation of cell-mediated and up-regulation of antibody-mediated immunity commensurate to the trauma. ,

5.

(1997) Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo a potential role for leukocyte trafficking,

6.

(1996) Stress-induced changes in blood leukocyte distribution. Role of adrenal steroid hormones,

7.

(1995) Effects of stress on immune cell distribution,

8.

(1999) The time dimension in stress responses relevance for survival and health,

9.

(1987) Noradrenergic sympathetic neural interactions with the immune system,

10.

(1992) The Manual of Laboratory and Diagnostic Tests, Lippincott Williams & Wilkins

11.

(1997) In vivo the environmental pollutants lead and mercury induce T cell responses skewed toward type-2 reactivities,

12.

(1998) The restraint stress drives a shift in Th1/Th2 balance toward Th2-dominant immunity in mice,

13.

(1996r192-8) Corticosterone modulates behavioral and metabolic effects of lipopolysaccharide ,

14.

(1995) The protective role of the hypothalamic-pituitary-adrenal axis against lethality produced by immune, infectious, and inflammatory stress.,

15.

(2001) Relationships between IFN and Listeria monocytogenes pathogenesis in BALB/c mice,

16.

(1994) Salivary cortisol in psychoneuroendocrine research,

17.

(2000189-201) Central/Peripheral nervous system and immune responses.,

18.

(1997) The role of adrenocorticoids as modulators of immune function in health and disease: neural, endocrine and immune interactions.,

19.

(1995) Interaction of the nervous and immune systems in development, normal brain homeostasis, and disease. ,

20.

(2001) Quantitative aspects of stress-induced immunomodulation,

21.

(1999) Endogenous glucocorticoids protect against cytokine-mediated lethality during viral infection ,

22.

(1997) Differential expression of the beta2-adrenergic receptor by Th1 and Th2 clones implications for cytokine production and B cell help Journal of Immunology,

23.

(2000) Saliva in health and disease:an appraisal and update,

24.

(1997) Neural-immune interactions in health and disease,

25.

(1999) Regulation of the hypothalamic-pituitary-adrenal axis by cytokines actions and mechanisms of action,

한국심리학회지: 건강

논문 투고 OA 정책