스트레스 호르몬인 타액 코티졸과 자기보고식 스트레스 척도 점수 사이의 관계
The Relationship between the stress hormone, salivary cortisol level and stress score by self-report measurement
정연수 (공군사관학교)
박세권 (공군사관학교)
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초록
건강한 젊은 남자, 여자인 사관생도를 대상으로 심리적 스트레스 정도와 스트레스의 생리적 척도 중 하나인 타액 내 코티졸을 정량하여 비교 분석함으로서 만성적 생활스트레스의 척도간 상관관계를 연구하였다. 타액 코티졸의 양과 스트레스 총점에서의 개인차는 정적 상관성(r=0.319)을 나타내었으나 호환성은 없었다. 그러나 타액 코티졸의 양이 상대적으로 높은 상위 25%에 해당하는 개인들의 스트레스 총점과 타액 코티졸을 비교했을 때 상관계수가 r=0.626으로 높은 상관성을 나타내었다. 즉 건강한 집단에서 자기보고식 스트레스 척도는 생리적 척도와 직접 비교되지 못하나 상대적으로 높은 생활 스트레스(>8.5 ng/ml 타액 코티졸)를 경험하는 조건에서는 상호호환이 가능함을 보고한다. 또한, 심리적 스트레스가 상대적으로 높았던 2학년 생도들이 3학년 생도들에 비하여 유의미하게 높은 타액 코티졸 수준을 보이며 (p<0.002), 반대로 유의미하게 낮은 수의 백혈구(p<0.02), 적혈구(p<0.03)를 보유하고 있었다. 스트레스 정도가 심한 2학년 집단은 정상수치보다 낮은 혈구를 가지고 있음으로서 스트레스의 생리적 반응이 정상상태에서도 면역기능과 연관됨을 알 수 있었다.
- keywords
- life stress, salivary cortisol, psychoneuroimmunology, leukocytes, life stress, salivary cortisol, psychoneuroimmunology, leukocytes, 생활스트레스, 타액 코티졸, 심리신경면역, 혈구세포
Abstract
We investigated correlation between psychological stress level and one of the physiological stress biomarkers, salivary cortisol level of healthy men and women, cadets of Air Force Academy. Salivary cortisol level of individuals correlated positively with psychological stress test score (r=0.319), but it could not compatible in normal healthy individuals. On the contrary, salivary cortisol level correlated highly with psychological stress test score in individuals, who belongs to the upper 25% group based on their salivary cortisol level (r=0.626). We report that psychological stress score based on self reporting and salivary cortisol level may not be compatible in healthy men and women, however, quantitative scales come from both of measurements can be used for same purpose in some of healthy individual with relatively higher stress level(>8.5 ng/ml cortisol). In comparison between groups, second grade cadets with relatively higher score in psychological stress test had significantly higher salivary cortisol level than third year cadets with relatively low stress score in psychological stress test (p<0.002). Second grade cadets had significantly lower number of white blood cells (p<0.02) and red blood cells (p<0.03) than third year cadets. We supposed that physiological reponses against to life stressors may relate to immunity in normal situation because second grade cadets represented higher stress level had lower number of blood cells.
- keywords
- life stress, salivary cortisol, psychoneuroimmunology, leukocytes, life stress, salivary cortisol, psychoneuroimmunology, leukocytes, 생활스트레스, 타액 코티졸, 심리신경면역, 혈구세포
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