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The relationship of depression level and depression factors to neuro-cognitive functions in neurological outpatients

The Korean Journal of Health Psychology / The Korean Journal of Health Psychology, (P)1229-070X; (E)2713-9581
2008, v.13 no.2, pp.445-459
https://doi.org/10.17315/kjhp.2008.13.2.009


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Abstract

The purpose of this study investigated the differences of depression figure according to diagnosis, and the relation of depression level and depression factors to neuro-cognitive functions. The subjects were 142 patients diagnosed as Alzheimer disease, vascular dementia and mild cognitive impairment. The patients were given brain MRI, neurological examination, the Seoul Neuro-psychological Screening Battery(SNSB), the geriatric depression scale(GDS) and the activity of daily living scale (ADL). The depression rate of Alzheimer patients were the highest compared with other group. However, the vascular dementia showed the highest depression level. In higher depression level, there were significantly lower in attention abilities, psychomotor velocities, visual memory, executive function and ADL. The results of factor analysis for the GDS was classified 4 factors such as depression, worry, dysphoria, and apathy. The depression factor of GDS was related to the attention, immediate visual recall, and executive function. On the other hand, the apathy factor was related to the core symptoms of dementia, such as recall and recognition of memory. Because the depressive symptoms of the dementia patients were often originated from both emotional reaction to their defect and neurological disease itself, the factors of depression might be affected by causes of dementia. So, it is important to ensure that the dementia patients with depression need appropriate treatment through the evaluation of depression factors.

keywords
우울수준, 우울 요인, 무감동 요인, 신경인지기능, 일상생활기능, depression level, depression factor, apathy factor, neuro-cognitive functions, daily activity, depression level, depression factor, apathy factor, neuro-cognitive functions, daily activity

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The Korean Journal of Health Psychology